The United States slapped sanctions on Syrian President Bashar Assad and six senior Syrian officials for human rights abuses over their brutal crackdown on anti-government protests, for the first time personally penalizing the Syrian leader for actions of his security forces.
The White House announced the sanctions Wednesday, a day before President Barack Obama delivers a major speech on the uprisings throughout the Arab world. The speech is expected to include prominent mentions of Syria.
The Obama administration had pinned hopes on Assad, seen until recent months as a pragmatist and potential reformer who could buck Iranian influence and help broker an eventual Arab peace deal with Israel.
But U.S. officials said Assad's increasingly brutal crackdown left them little choice but to abandon the effort to woo Assad, and to stop exempting him from the same sort of sanctions already applied to Libya's Moammar Gadhafi.